Main ingredient: Curcumin
Cholesterol has an important task in our bodies to carry out a variety of biological processes, but if you have too much of it in the body, it can potentially cause heart disease. The worst problem with high cholesterol is that you usually don't even know you have it, unless you've had your cholesterol recently tested. There are many things to know about this silent, yet potentially deadly, condition.
Curcumin, the dietary polyphenol isolated from turmeric can inhibit cholesterol uptake in the enterocytes by inhibiting the expression of NPC1L1, the key transporter of cholesterol in the cell membrane.
Curcumin is one of the principle curcuminoids of the spice turmeric. Its antioxidant, anti-cancer and anti-inflammatory effects have been intensively studied. Previous in vivo studies showed that administration of curcumin also decreased cholesterol levels in the blood, and the effects were considered to be related to upregulation of LDL receptor.