Main ingredient: Hoodia gordonii in combination with fish oils
Chewing gum containing an extract of Hoodia gordonii and 2-hydroxyoleic acid and is directed to treatment of obesity, hypertension and metabolic disorders.
In the last years, hoodia has been heavily marketed for weight loss and has become immensely popular.
There has always been a demand for diet pills and supplements. After the ban on the herb ephedra, the market is ripe for a chewing gum containing hoodia for appetite suppression.
The myth behind hoodia's popularity comes from the Bushmen of the Kalahari desert who are said to rely on hoodia to ward off hunger and thirst during long hunting trips.
The only active ingredient is a steroidal glycoside that has been called "p57". Currently, only hoodia gordonii is thought to contain p57.
A study published in Brain Research found that injections of p57 into the appetite center of rat brains resulted in altered levels of ATP, an energy molecule that may affect hunger. The animals receiving the P57 injections ate less than rats that received placebo injections.
It has also been found to possess the ability to lower blood glucose levels and thereby be an attractive candidate for treating/preventing diabetes 10 and impaired glucose tolerance. The active ingredient identified so far is a steroidal glycoside also called P57. P57 appears to be safe and has no known side effects.